Everything about The International Union Of Basic And Clinical Pharmacology totally explained
The
International Union of Basic and Clinical Pharmacology (IUPHAR) is a voluntary, non-profit association representing the interests of scientists in
pharmacology-related fields to facilitate
Better Medicines through Global Education and Research around the world.
History
Established in 1959 as a section of the International Union of Physiological Sciences, IUPHAR became an independent organization in 1966 and is a member of the
International Council for Science (ICSU). The first World Congress of Pharmacology was held in
Stockholm,
Sweden in 1961 and subsequently held every three years. After 1990 the World Congresses were moved to a four-year interval. These meetings not only present the latest pharmacological advances in research accomplishments, technology, and methodology, but also provide a forum for international collaboration and exchange of ideas. A General Assembly, consisting of delegates from all the member societies, is convened during the congresses so member societies have an opportunity to elect the Executive Committee and vote on matters concerning the governance and activities of the union.
Composition
IUPHAR members are national societies from around the world, however, the various sections and committees are composed of individuals from
academia,
pharmaceutical companies, and government organizations, all working together to advance the field. The Division of Clinical Pharmacology focuses on the needs and research tools for clinicians. The Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR) facilitates the interface between the discovery of new sequences from the
Human Genome Project and the designation of the derived proteins as functional receptors and ion channels. In other words, as new discoveries are made in pharmacology, NC-IUPHAR provides a uniform guideline for naming and classifying the results in the public domain. Sections specializing in various areas of pharmacology have been established, including Teaching,
Drug metabolism,
Gastrointestinal Pharmacology,
Natural Products, and
Pharmacogenetics.
Activities
In general, IUPHAR offers individual pharmacologists free curriculum expertise, career development and job listings, research resources, and collaboration opportunities (http://www.iuphar.org). IUPHAR offers its member societies venues for participating in world-wide initiatives, publicizing member meetings and activities, nominating individuals for Young Investigator awards, and naming delegates to the General Assemblies. For examples, visit the biannual newsletter entitled,
Pharmacology International at http://www.iuphar.org/pubs_newsletter.html .
A primary purpose of IUPHAR is providing global free access to a major, on-line repository of characterization data for
receptors and
drugs through the Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR, http://www.iuphar-db.org), which was established in 1987. This database includes all the
G protein-coupled receptors,
voltage-gated ion channels, 7TM receptors,
nuclear receptors and, shortly,
ligand-gated ion channels which are known to be in the
human genome. Where relevant, data on the rat and mouse
homologues are presented to assist researchers and clinicians in developing and/or enhancing therapeutics for eventual medication for humans.
As a
non-government organization in official relations with the
World Health Organization (WHO), IUPHAR representatives help shape international policy on
essential medicines, appropriate dose therapeutics for children, and
clinical pharmacology core competencies among its many WHO-related activities.
The Division of Clinical Pharmacology compiled and released the Research in Humans Compendium (http://www.iuphar.org/clin_hu.html), a free resource to provide the scientific community interested in human research with an easy-to-use reference on how to design a research
protocol to assess the effectiveness of a drug in a series of pathological conditions.
An important aspect of IUPHAR is the development of pharmacology in
developing countries. In conjunction with the
International Council for Science, the Pharmacology for
Africa (Phar
fA, http://www.iuphar-africa.org/) initiative was undertaken in 2006 to promote and organize pharmacology on the African continent. The South African Society of Basic and Clinical Pharmacology is building a database and network of institutions and pharmacologists to create an infrastructure for training and funding pharmacologists. The long-term goal is for the African continent to attain the necessary pharmacological knowledge and resources to address the disease-related issues affecting the population.
Future Directions
The early years of the 21st century will be focused on integrating basic and clinical research into a continuous spectrum of investigation to implement
translational medicine techniques more quickly. The 9th World Conference on Clinical Pharmacology and Therapeutics in
Québec City,
Canada (http://www.cpt2008.org) will be the last IUPHAR meeting to present clinical pharmacology separately. The WorldPharma 2010 World Congress of Pharmacology (http://www.worldpharma2010.org) in
Copenhagen,
Denmark will be the first completely integrated meeting. The expectation of merging these different approaches to the same discipline is to more quickly discover, devise, test and introduce new or higher quality therapeutics for humans.
Educational components will be emphasized for both existing pharmacology programs through an international initiative in Integrative and Organ Systems Pharmacology, as well as increasing and enhancing pharmacology training in developing countries through the Teaching Section. This topic will be a central theme of the XVIIth World Congress of Pharmacology being held in Cape Town, South Africa in 2014 (http://www.iuphar2014.org).
Further Information
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